Diarrhea (diarrhea) - frequent bowel movements or one-time allocation of liquid faeces (usually more than 200-300 g per day).
At the heart of diarrhea may be based on an increase in active secretion of intestinal sodium and water retention, increased osmotic pressure in the oral ulcers (decreased absorption of water and eletrolitov), violations of peristalsis, increased exudation of water and electrolytes into the lumen of the intestine. Excess secretion in the small intestine develops in its colonization of pathogenic microorganisms (eg, cholera vibrios, ente-ropatogennymi viruses), with tumors that produce peptide hormones, syndrome Zollinger-Ellison (due to increased production of gastrin). Excess secretion in the colon is possible with malabsorption in the small intestine of fatty acids with long chains of bile acids (for example, dysbacteriosis). Hyperosmotic diarrhea develops with malabsorption (eg celiac disease), deficiency of pancreatic enzymes (in chronic pancreatitis, pancreatic cancer) and bile salts (with obstructive jaundice), under the action of osmotic laxatives (magnesium sulfate, lacto-vine).
Violations peristalsis possible with irritable bowel syndrome, under the influence of some laxatives (senna extract, Bisacodyl, castor oil). Increased exudation of water and electrolytes is accompanied by exudation of protein into the lumen through the gut mucosal damage – with Crohn’s disease, ulcerative colitis, intestinal tuberculosis, intestinal infections (dysentery, salmonellosis), malignant tumors and ischemic bowel disease.
Symptoms, diarrhea (diarrhea)
Frequency of stool varies, feces – watery or mushy. When gipersekretornoy diarrhea stools copious and watery, with hyperosmotic – prevails polifekaliya (increase in the number of faeces from undigested residues), with motor diarrhea occurs slim frequent loose stools, with stools giperekssudativnoy fluid, sometimes mixed with pus and blood. The nature of defecation depends on the disease.
Thus, the presence of fresh or altered blood in the stool indicates pathology of the colon, the appearance of pus and mucus – in the inflammatory process. In particular, when dysentery stool has a dense consistency first, then becomes a liquid, scanty, it appears mucus and blood in amoebiasis – contains a glassy mucus and blood and sometimes mucus and blood pervades feces become kind of raspberry jelly.
In diseases of the pancreas indicated "fat" calories (after rinsing faeces on the toilet are drops of fat).
There are acute diarrhea (lasting less than 2-3 weeks) and chronic (lasting more than 3 weeks). The causes of acute diarrhea usually are infectious (dysentery, salmonellosis, etc.) and other inflammatory bowel disease (ulcerative colitis, Crohn’s disease), intake of medicines (laxatives, antibiotics, antacids containing magnesium salts, etc.).
For acute infectious diarrhea are typical signs of intoxication, fever, anorexia, sometimes – vomiting. The cause of diarrhea, continuing after acute gastroenteritis, can be persistent infection (giardiasis, iersenioz) acquired lactase deficiency, irritable bowel syndrome, as well as previously unrecognized disease (eg, celiac disease, ulcerative colitis).
Chronic diarrhea may be a manifestation of functional disorders or organic bowel disease, including irritable bowel syndrome, colon cancer, ulcerative colitis, Crohn’s disease, malabsorption syndrome, etc. Pain in gipogastrii may accompany diarrhea in diseases of the colon (diverticulosis, Crohn’s disease, irritable colon tumors of the colon), in the upper half of the stomach – with pancreatitis, Zollinger-Ellison syndrome. Ulcerative colitis, and dysbiosis often manifested by diarrhea without pain. Fetid smell faeces, presence of undigested residues, feeling rumbling, transfusion, abdominal distension – nonspecific symptoms, occurring in many diseases.
Lightweight and non-durable diarrhea little effect on the general condition of patients, severe and chronic lead to dehydration, loss of electrolytes (potassium, sodium, magnesium), exhaustion, hypovitaminosis, pronounced changes in the organs. To determine the cause of diarrhea spend scatological and bacteriological study.
Treatment of diarrhea (diarrhea)
Treatment is directed primarily at addressing the causes of the diarrhea. For example, with pancreatic insufficiency shows enzymatic preparations – Creon, Festal, mezim forte and others have shown mechanically and chemically light diet with the exception of products that enhance motor evakuatornuyu and secretory function. In order to restore eubioza use of antibacterials, preference is given to drugs which do not disturb the equilibrium of the microbial flora in the intestines – Intetriks, nifuroxazide (ersefu-Rila), etc. Uses bacterial preparations – Bifidumbacterin, bifikol, laktobakterin, Bacto-SUB-T, lineks, enterol, flonivin BS and others, as well as hilak forte. As symptomatic treatment using calcium carbonate, bismuth preparations, tanalbin; decoctions of oak bark, grasses, hypericum, serpentine root, bloodroot, or burnet, wild cherry fruit, the infusion of blueberries, alder aggregate fruits, flowers, daisies, belladonna tincture, etc. Apply adsorb, binders, enveloping means (smectic, Tanna, PC, etc.). To slow intestinal peristalsis use spasmodicals (No-Spa, papaverine, bkus-Copan). Antidiarrheal destviem has loperamide (Imodium), lowering the tone and motility of the intestine through effects on opiate receptors. The drug is used in acute gastroenteritis, motor disorders, appointed in a dose of 4 mg by mouth after the first loose stool, then 2 mg after each bowel movement. In the development of dehydration is conducted infusion therapy or rehydration solutions (tsitroglyukosolan, Rehydron, tours) are appointed for oral administration.
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