Fibroids of the uterus is one of the most common benign tumors in women. Frequency of occurrence is strikingly high – one in four women older than 30 years and every third woman predklimakterichesogo age has given pathology. Approximately every second patient department of operative gynecology is scheduled surgery for uterine myoma.
Fibroids of the uterus or, more precisely, leiomyofibroma - smooth-tissue tumor of the uterus with a pronounced connective tissue component. Myoma (leiomyoma) of the uterus in its pure form is rare. Thus, fibroid with nodes located in the middle of the myometrium is the ratio of muscle and connective parts of 2:1 and more like a true myoma. In podbryuschinnyh nodes fibroids, the ratio is 1:3.
The causes of fibroids include, above all, the stimulating effect of hormonal background on the myometrium. Found that estrogen increased the background is not observed in all patients, but it develops metabolic functions of estrogens and yellow bodies, changing the sensitivity of the uterus to the action of hormones.
A role in the origin and development of uterine fibroids are violations in the hypothalamus – pituitary – ovary – uterus. Although no specific data in this regard, little, most authors agree on the idea that since the beginning of puberty before the start of menopause estrogen levels in the blood increases by about 3 times and this factor should be considered, if not causal, then one of the important starting points. It is important and heredity, ie in families where there were fibroids and polycystic ovarian risk of fibroids in direct relatives is much higher.
The development of uterine fibroids frequently characterized by the formation of multiple units of various sizes. Single units are rare. The most frequent localization of nodes – in the midline, near the pipe spools and lateral parts of the cervix, where there is a close intertwining of muscle fibers. Quite often, the node starts to grow inside the muscular layer. For the limits of uterine fibroids often grow on the muscle pedicle. Sometimes the leg is so thin that it can twist and cause complications of the disease. Simple myoma, myoma and proliferating predsarkoma usually are stages of development of malignant disease – sarcoma, but because timely treatment of fibroids is the most effective way to prevent the development of leyomiosarkomy.
Clinic fibroids
The clinic depends on the type of tumor growth, its localization and some other factors. With slow growth node disease for years can take place without any manifestations, despite the relatively large size of fibroids by the time of its detection. The rapid growth of the tumor gives a more pronounced symptoms, therefore, such patients enter the surgical department after 1-2 years of onset.
Patients go to the doctor when they detect bleeding associated with its anemia, abdominal pain, symptoms of the bladder and other adjacent organs. Bleeding is usually manifested in the form of heavy monthly (with clots, more than 5 days), but then can be transformed into cases of bleeding out monthly.
With long-term course of the disease caused disturbances of ovarian function up to the lack of ovulation or luteal dysfunction, which leads to even more pronounced hormonal shifts. These shifts are considered to be a stimulating factor in the development of cystic changes in the ovaries, and endometrial hyperplasia. With the onset of menopause, a decrease tumor size. If the tumor size for the year increased by 5 weeks of pregnancy, the need for careful examination to exclude malignant transformation of uterine sarcoma.
Diagnosis of fibroids
The diagnosis is easily already in the normal gynecological examination. If you suspect submucosa fibroids sometimes necessary hysteroscopic examination (examination of the uterus).Great importance in diagnosis are the means of medical imaging, among which played a leading role ultrasonography. Are also used magnetic resonance imaging, X-ray and some other methods.
Treatment of fibroids
Predominantly surgery. Now try to apply organ-saving operations. However, the rapid growth of the tumor, suspicion of malignancy, large size of the tumor carrying out radical surgery: amputation of the uterus, ektirpatsiya uterus.
But modern surgery can remove even large fibroids laparoscopically, which creates additional opportunities for the treatment of a doctor and patient. Sometimes you can do without surgical intervention. In these cases, pharmacological inhibition of tumor growth through an integrated treatment of hormonal and nonhormonal drugs.
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